What is Nystain CAS 1400-61-9? Nystatin is an antifungal drug widely used to treat various diseases caused by fungal infections, especially Candida infections. Its CAS number is 1400-61-9. Now Jiaoze will explain the chemical properties, mechanism of action, clinical applications and precautions for using Nystatin.
Chemical properties of Nystatin
Nystatin is a polypeptide antibiotic produced by Streptomyces noursei. It has a complex structure, mainly composed of multiple amino acids, with multiple amino and carboxyl groups, which give it a wide range of biological activities. Nystatin has a significant inhibitory effect on many molds and yeasts, especially on various strains of Candida.
Mechanism of Action
Nystatin's antifungal mechanism of action is mainly through binding to sterols in the fungal cell membrane, resulting in increased cell membrane permeability, which causes the leakage of ions and small molecules in the cell, and ultimately leads to cell death. This mechanism of action makes Nystatin extremely effective in treating local infections, especially for Candida infections in the mouth and intestines.
Clinical Application
Nystatin is mainly used to treat oral, gastrointestinal and skin infections caused by fungi. Common usage scenarios include:
1. Oral Candida infection: In the treatment of oral Candida infections (such as thrush), Nystatin can be used as the first choice drug, and patients usually use gargles or oral suspensions.
2. Intestinal Candida infection: For secondary infections caused by long-term use of antibiotics, Nystatin as an oral drug can also effectively inhibit the growth of Candida in the intestine.
3. Skin infection: Nystatin can also be used for local treatment of some skin fungal infections, usually in the form of creams or ointments.
Precautions for use
Although Nystatin is very effective in antifungal treatment, the following points should still be noted when using it:
4. Allergic reactions: Some patients may have allergic reactions to Nystatin, and medical history should be evaluated before use.
5. Side effects: Although Nystatin is generally well tolerated, it may cause mild gastrointestinal discomfort such as nausea, vomiting, or diarrhea.
6. Duration of use: Antifungal treatment usually requires persistence for a period of time, and medication should be continued even if symptoms are relieved to ensure that the infection is completely cleared.
From the above, it can be seen that Nystatin, as a safe and effective antifungal drug, has relieved the pain caused by fungal infections for many patients in clinical practice. However, reasonable use and attention to potential side effects are the key to ensuring successful treatment. Therefore, before using Nystatin, fully communicating with medical staff and understanding the indications and methods of use of the drug will help achieve the best treatment effect.
